December 2018 (None)
November 2018 Grantees
Luisa Escobar Hoyos, PhD
Title: Research Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Altered mRNA splicing dependent on mutant p53 identifies novel therapeutic vulnerability in pancreatic cancer
Awarding Agency:
National Cancer Institute
Kyrie Pappas, PhD
Title: Research Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Charles L. Sawyers, MD
Project Title: INVESTIGATING THE MOLECULAR BASIS OF OLAPARIB RESISTANCE IN BRCA2-DEFICIENT PROSTATE CANCER
Awarding Agency:
National Cancer Institute
Yuchen Xie, B.S.
Title: Graduate Student
Department/Program: Gerstner Graduate School of Biomedical Sciences
Lab Head: Emily Chen, MD, PhD
Project Title: The Role of Epigenetic Tumor Suppressors in Regulating Tumorigenesis and Tumor-Immune Crosstalk
Awarding Agency:
National Cancer Institute
October 2018 Grantees
Erik Ladewig, PhD
Title: Research Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Maurizio Scaltriti, PhD
Project Title: Evolutionary resistance of metastatic breast cancer
Awarding Agency:
National Cancer Institute
Pavak Kirit Shah, PhD
Title: Research Scholar
Department/Program: Developmental Biology
Lab Head: Zhirong Bao, PhD
Project Title: Understanding the developmental mechanisms that ensure robustness in neuronal patterning
Awarding Agency:
Eunice Kennedy Shriver National Institute of Child Health and Human Development
Ly Vu, PhD
Title: Research Associate
Department/Program: Molecular Pharmacology
Lab Head: Michael Kharas, MD
Project Title: Translational Regulation by RNA Regulating Proteins in Leukemia
Awarding Agency:
National Cancer Institute
September 2018 Grantees
Stephen Jannetti, PhD
Title: Graduate Student
Department/Program: Radiology
Lab Head: Thomas Reiner, PhD
Project Title: Development of Astatine-211-labelled PARP Inhibitor for Targeted Radiotherapy
Awarding Agency:
The Tow Foundation
Simon Schwoerer, PhD
Title: Research Fellow
Department/Program: Cancer Biology & Genetics
Lab Head: Craig B. Thompson, MD
Project Title: Deciphering metabolic rewiring of cysteine metabolism for redox control in cancer cells
Awarding Agency:
Human Frontier Science Program
Neta Shlezinger, PhD
Title: Research Scholar
Department/Program: Medicine
Lab Head: Tobias M. Hohl, MD, PhD
Project Title: LSRF Fellowship
Awarding Agency:
Life Sciences Research Foundation
August 2018 Grantees
Elham Azizi, PhD
Title: Research Fellow
Department/Program: Computational Biology
Lab Head: Dana Pe’er, PhD
Project Title: Integrative framework for identifying dysregulated mechanisms in the tumor-immune microenvironment
Awarding Agency:
National Cancer Institute
Nehemiah Cox, PhD
Title: Research Fellow
Department/Program: Immunology
Lab Head: Frederic Geissmann, MD, PhD
Project Title: Role of tissue resident macrophages in development of mammary tumors
Awarding Agency:
National Cancer Institute
Roozbeh Eskandari, PhD
Title: Research Fellow
Department/Program: Radiology
Lab Head: Kayvan R. Keshari, PhD
Project Title: Real-time Quantification of Metabolic Dynamics in Pancreatic Ductal Adenocarcinoma
Awarding Agency:
The Tow Foundation
King Hui, PhD
Title: Research Scholar
Department/Program: Cell Biology
Lab Head: Phillip Niethammer,PhD
Project Title: Investigating redox regulation of inflammation initiation by biosensor imaging
Awarding Agency:
The Tow Foundation
Susanne Kossatz, PhD
Title: Research Fellow
Department/Program: Radiology
Lab Head: Thomas Reiner, PhD
Project Title: Evaluation of PARP1 targeted imaging as screening tool for esophageal adenocarcinoma
Awarding Agency:
National Cancer Institute
Konrad H Stopsack, MD, PhD
Title: Research Associate
Department/Program: Medicine
Lab Head: Philip W. Kantoff, MD
Project Title: Cholesterol synthesis and statin therapy in prostate cancer
Awarding Agency:
Congressionally Directed Medical Research Programs
July 2018 Grantees
Kamal Menghrajani, PhD
Title: Hematology/Oncology Fellow
Department/Program: Medicine
Lab Head: Martin Tallman, MD
Project Title: Histone Methyltransferase Inhibitor (Pinometostat) with Azacitidine Combination Therapy in Patients with Relapsed/Refractory MLL-rearranged Acute Myeloid Leukemia
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
June 2018 Grantees
Kosuke Funato, PhD
Title: Research Associate
Department/Program: Neurology
Lab Head: Viviane Tabar,MD
Project Title: Dissecting the oncogenic role of histone mutations by human embryonic stem cell-based model system
Awarding Agency:
New York Stem Cell Foundation
Shun Lin, PhD
Title: Research Scholar
Department/Program: Immunology
Lab Head: Ming Li, PhD
Project Title: Anti-Tumor Immunity Unleased by Innate Immune Sensing of Self-DNA
Awarding Agency:
Cancer Research Institute
Sydney Lu, PhD
Title: Fellow
Department/Program: Immunology
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Understanding and Targeting SF3B1 Mutations in CLL
Awarding Agency:
Aplastic Anemia & MDS International Foundation, Inc.
Alejandro Sanchez, PhD
Title: Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Timothy A. Chan, PhD
Project Title: Mechanistic Underpinnings of Sarcopenia and Adverse Outcomes in Renal Cell Carcinoma
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
Kaloyan Tsanov, PhD
Title: Research Scholar
Department/Program: Cancer Biology & Genetics
Lab Head: Scott W. Lowe, PhD
Project Title: The Role of Ribosomal Protein Gene Deletions in Liver Cancer
Awarding Agency:
Jane Coffin Childs Memorial Fund
Neil Vasan, MD
Title: Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: José Baselga, MD, PhD
Project Title: Discovery and Validation of Tandem Mutations Driving Cancer
Awarding Agency:
Brown Performance Group
Rocio Vicario, PhD
Title: Research Scholar
Department/Program: Immunology
Lab Head: Frederic Geissmann, MD, PhD
Project Title: Signaling pathways driving histiocytic neoplasms
Awarding Agency:
American Association for Cancer Research
Allison Warner, PhD
Title: Fellow
Department/Program: Gerstner Graduate School of Biomedical Sciences
Lab Head: Jedd D. Wolchok, MD, PhD
Project Title: Regulation of Immune Activation and Response in Cancer: Implications for Immunotherapy
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
Elizabeth Wasmuth, B.S.
Title: Research Scholar
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Charles L. Sawyers, MD
Project Title: Structural and functional studies of androgen receptor and its cofactors
Awarding Agency:
Congressionally Directed Medical Research Programs
May 2018 Grantees
Rajiv Agarwal, MD
Title: Fellow
Department/Program: Medicine
Lab Head: Leonard Saltz, MD
Project Title: Evaluating the Impact of Proactive Palliative Care in Patients Initiating Phase I Targeted or Immune-Based Cancer Therapeutics: A Randomized Controlled Trial
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
Luisa Escobar Hoyos, PhD
Title: Research Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Aberrant RNA processing induced by mutant p53 in pancreatic cancer: mechanistic and therapeutic implications
Awarding Agency:
National Pancreas Foundation
Niloufer Khan, MD
Title: Hematology/Oncology Fellow
Department/Program: Lymphoma Service
Lab Head: Steven Horwitz, MD
Project Title: Impact of intestinal microbiome on outcomes after autologous transplant for hematologic malignancies
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
Richard Jirui Lin, MD, PhD
Title: Fellow
Department/Program: Medicine
Lab Head: Sergio A. Giralt, MD
Project Title: A Pilot Study of Geriatric Assessment and Neurocognitive Evaluation for CAR T-cell in Older Patients
Awarding Agency:
Pardee Foundation, Elsa U.
Sydney Lu, PhD
Title: Fellow
Department/Program: Immunology Program
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Therapeutic Targeting of RNA Splicing Factor mutant Leukemias via Inhibiting Protein Arginine Methylation
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
Michael Ortiz, PhD
Title: Special Fellow
Department/Program: Pediatrics
Lab Head: Andrew Kung, MD,PhD
Project Title: Targeting prohibitin-induced therapy resistance in Wilms Tumor
Awarding Agency:
Hyundai Hope On Wheels
Jessica Tao, PhD
Title: Fellow
Department/Program: Medicine
Lab Head: David Hyman, MD
Project Title: Augmenting the Immune Response to Checkpoint Blockade with PARP Inhibition in Tumors with Homologous Recombination Deficiency
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
Neil Vasan, MD
Title: Medical Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: José Baselga, MD, PhD
Project Title: Dual compound PIK3CA mutations in the pathogenesis and treatment of metastatic breast cancer
Awarding Agency:
Conquer Cancer Foundation of the American Society of Clinical Oncology
April 2018 Grantees
Sangmoo Jeong, PhD
Title: Research Scholar
Department/Program: Radiology
Lab Head: Kayvan R. Keshari, PhD
Project Title: Hyperpolarized Micro-NMR for Quantitative Analysis of Metabolism in Leukemia Stem Cells
Awarding Agency:
National Cancer Institute
Paola Vinci, PhD
Title: Research Fellow
Department/Program: Medicine
Lab Head: Alan Hanash, PhD
Project Title: The role of Interleukin 22 in tissue protection and regeneration after hematopoietic stem cell transplantation
Awarding Agency:
American Society for Blood and Marrow Transplantation
March 2018 Grantees
Benjamin Durham, PhD
Title:
Department/Program: Pathology
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Cellular Origins, Molecular Pathogenesis, and Novel Therapeutic Strategies for MAP Kinase-Driven Hematological Malignancies
Awarding Agency:
National Cancer Institute
Michael Marco, MD, M.Sc.
Title: Research Fellow
Department/Program: Surgery
Lab Head: Julio Garcia-Aguilar, MD, PhD
Project Title: Immunological Landscape Associated with KRAS Mutation in Colorectal Cancer
Awarding Agency:
American Society of Colon and Rectal Surgeons
Michael Ortiz, MD
Title: Special Fellow
Department/Program: Pediatrics
Lab Head: Alex Kentsis, MD, PhD
Project Title: Targeting prohibitin-induced therapy resistance in Wilms tumors
Awarding Agency:
Pediatric Cancer Research Foundation
Ly Vu, PhD
Title: Research Associate
Department/Program: Molecular Pharmacology
Lab Head: Michael Kharas, MD
Project Title: Defining Translation Regulation by RNA binding protein SYNCRIP in Acute Myeloid Leukemia
Awarding Agency:
Leukemia and Lymphoma Society
Matthew Wipperman, PhD
Title: Research Scholar
Department/Program: Immunology Program
Lab Head: Michael Glickman,MD
Project Title: Microbiomic Correlates of Tuberculosis Infection and Antimycobacterial Treatment
Awarding Agency:
Clinical and Translational Science Center
February 2018 Grantees
Shawn Dason, MD, FRCSC
Title: Urologic Oncology Fellow
Department/Program: Surgery
Lab Head: David B. Solit, MD
Project Title: Phylogenetic Analysis of Chemotherapy-Resistant Urothelial Carcinoma of the Bladder
Awarding Agency:
American Urological Association Foundation
Benjamin Durham, PhD
Title: Research Fellow
Department/Program: Pathology
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Defining the Cell-of-Origin of Erdheim-Chester Disease
Awarding Agency:
Erdheim-Chester Disease Global Alliance
Laura Elizabeth Feeney, PhD
Title: Research Fellow
Department/Program: Molecular Pharmacology
Lab Head: John Petrini, PhD
Project Title: The tumor suppressive barrier in response to oncogenes: MRN-complex dependent genome rearrangements to prevent tumorigenesis and metastasis
Awarding Agency:
Metastasis and Tumor Ecosystems Center
Thomas J. Gardner, PhD
Title: Research Fellow
Department/Program: Molecular Pharmacology
Lab Head: David A. Scheinberg, MD, PhD
Project Title: Creating a targeted micropharmacy for improved cellular cancer therapies
Awarding Agency:
National Cancer Institute
Linda Miles, PhD
Title: Research Fellow
Department/Program: Medicine
Lab Head: Charles Rudin, MD, PhD
Project Title: Interrogating the functional contributions of RAS mutations in AML
Awarding Agency:
Leukemia and Lymphoma Society
William Yewdell, PhD
Title: Postdoctoral Fellow
Department/Program: Immunology
Lab Head: Jayanta Chaudhuri, PhD
Project Title: The role of RNA-dependent AID targeting in class switch recombination and B cell lymphomagenesis
Awarding Agency:
Leukemia and Lymphoma Society
January 2018 Grantees
Elham Azizi, PhD
Title: Research Fellow
Department/Program: Computational Biology
Lab Head: Dana Pe’er, PhD
Project Title: Characterizing tumor
heterogeneity in Acute Myeloid
Leukemia
Awarding Agency:
American Cancer Society
Christopher Sultan Hackett, MD, PhD
Title: Fellow
Department/Program: Medicine
Lab Head: Renier J. Brentjens,MD, PhD
Project Title: Optimizing CAR T-cell therapy in a clinically-relevant murine model of lung cancer
Awarding Agency:
Druckenmiller Center for Lung Cancer Research
Stefan Kiesgen, PhD
Title: Research Fellow
Department/Program: Surgery
Lab Head: Prasad S. Adusumilli, MD
Project Title: Next-gen CAR T cells resistant to lung cancer-mediated immunoinhibition
Awarding Agency:
Druckenmiller Center for Lung Cancer Research
Stanley Chun-Wei Lee, PhD
Title: Research Fellow
Department/Program: Human Oncology & Pathogenesis (HOPP)
Lab Head: Omar I. Abdel-Wahab, MD
Project Title: Defining and targeting novel genetic dependencies in
spliceosome-mutant leukemia
Awarding Agency:
American Society of Hematology
Nathalie Saurat, PhD
Title: Postdoctoral Fellow
Department/Program: Developmental Biology
Lab Head: Lorenz Studer, MD
Project Title: Identifying novel "induced aging" strategies to model neurodegeneration in human pluripotent stem cell models of Alzheimer's disease
Awarding Agency:
Glenn Foundation for Medical Research
Neta Shlezinger, PhD
Title: Research Scholar
Department/Program: Medicine
Lab Head: Tobias M. Hohl, MD, PhD
Project Title: Stony Wold-Herbert Fellowship
Awarding Agency:
Stony Wold-Herbert Fund, Inc.
Daochun Sun, PhD
Title: Research Fellow
Department/Program: Cancer Biology & Genetics
Lab Head: Luis Parada,PhD
Project Title: Cancer Stem Cells promote MPNST relapse after chemotherapy
Awarding Agency:
Boston Children's Hospital